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doi: 10.1016/j.isci.2022.103871 260 PpuloHBoaventuraPVinagreJBatistaRMendesACaldasRet al

[] Interestingly, based on propofol's pharmacokinetic and pharmacodynamic characteristics and being a high lipophilic medication with rapid CNS penetration, and fast redistribution, this may have resulted in faster metabolic clearance and led to shorter duration and incidence of withdrawal symptoms