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Description

J Clin Endocrinol Metab 101(4):17541761

Madeleine Giaquinto is director of regulatory affairs at Greenleaf Health, an FDA regulatory consulting company based in Washington, DC

The TRIUMPH-4 Phase 3 trial in obesity with knee osteoarthritis (Bays et al., NEJM 2025) reported 28.7% mean weight loss at 68 weeks at the 12 mg dose, plus a 75.8% reduction in WOMAC knee pain scores