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Signature M2 genes like Serpinb2 and Ccl11 were downregulated following nanoparticle treatment, while signature M1 differentiation genes, like Ccl5 , were upregulated

Purpose Because vaccines are often given to healthy persons, benefit-risk assessments are conducted to ensure that the benefits of vaccines, such as preventing infection, outweigh possible side-effect risks, such as vaccine-attributable myocarditis/pericarditis (inflammation of the heart or of the membrane surrounding the heart, respectively)

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