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Eligible patients were between 50 and 80 years of age with reproducible glaucomatous visual field loss in at least one eye, but no advanced visual field loss, that is, mean deviation values better than -16 decibels, visual acuity 0.5 (corresponding to 20/40), mean IOP less than 31 mmHg, or any IOP less than 35 mmHg

En regiones como los continentes africano y asitico y la cuenca mediterrnea existe una alta frecuencia de las diferentes variantes de la deficiencia enzimtica, mientras que en China y Japn la frecuencia es baja 23

The erectile response in the PT-141/sildenafil combination group was significantly better than for sildenafil alone [12]

Con el tiempo, las evidencias cientficas no dejan tan clara su utilidad