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The increased presence of pro-inflammatory cytokines, along with elevated levels of HIF-1, stimulates the synthesis of pro-angiogenic factors such as VEGF, EGF, IL-1, IL-8, CCL-28, and CCL-21 by macrophages, T cells, and FLSs within the RA joint

Here are some of the best supplements to consider taking alongside pure reduced glutathione : Vitamin C: The perfect partner Vitamin C is a water-soluble antioxidant that works synergistically with glutathione