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Bigman G

Representative Gene Ontology (GO) biological process categories were selected to remove redundancy and reported alongside the ATAC-seq DAR clusters

As TSH-stimulated T4 is synthesized and released into the bloodstream from the thyroid gland, it negatively feeds back to the hypothalamus, slowing the production of TSH releasing hormone (TSH-RH), putting a brake on TSH release from the pituitary, and consequently dampening the entire thyroid-synthesizing machinery in the thyroid gland

doi: 10.1210/jcem.84.12.6283

In Experiment 2, non-parametric analyses, Wilcoxon signed-rank test and KruskalWallis H Test, with pairwise post hoc analysis, and Spearmans correlation were performed for behavioral scores and MRS metabolite concentrations, as data were not normally distributed and of unequal sample size