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FIGURE 2 The primary ROS produced by the ETC is superoxide, a free radical with moderate reactivity, whose generation can lead to more reactive or secondary ROS derivatives

*Correspondence: Agata Blazewicz, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In terms of drug effects in epigenetic pharmacology, the influence of DNA methylation is being explored, which provides us with a new perspective to understand and treat cardiovascular diseases

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