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A general trend in the literature suggests that CB 1 R density decreases throughout the brain with aging, however, receptor function seems to differentially change depending on the region and cell type (Mato and Pazos, 2004

When applied, hyaluronic acid penetrates the skin, providing deep hydration and plumping effects that can reduce the appearance of fine lines and wrinkles

doi: 10.4161/23723556.2014.975093

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To improve the selectivity, in this work, we design and synthesize a malononitrile-functionalized TPE derivative, TPE-DCV, which can undergo addition reaction with thiol group to the alkene bond, leading to the change in its fluorescence in the system (Figure 1)