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doi: 10.1016/j.siny.2018.07.005 35 BattersbyCSanthalingamTCosteloeKModiN

Obstruction of the ureter leads to ferroptosis in renal tubular epithelial cells, which in turn causes the secretion of various fibrogenic factors and affects interstitial fibroblasts in a paracrine manner, promoting their proliferation and differentiation (128)