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The derivatization protocol for the quantification of TMA was an adaptation of the protocol described by Samples for TMAO levels quantification were prepared as follows: an amount of 25 L of each sample was collected, and 3 L of D9-TMAO (5 M concentration) and 122 L of a cold acetonitrile:methanol mixture (50:50, v/v) were added for protein precipitation

Mitochondrial oxidative phosphorylation regulates the fate decision between pathogenic Th17 and regulatory T cells

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Diagnosing TMAU by smell alone is frequently challenging, as the episodes of foul odour associated with the condition are often intermittent and episodic, depending on nutrition during the preceding 24-hour period [14]

Cytokines, as important mediators of immune and inflammatory pathways, communicate the function of distant organs, such as the digestive system and the central nervous system (201)