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Institute of Medicine says, Since 10-30% of older people may malabsorb food-bound B12, it is advisable for those older than 50 to meet their RDA mainly by consuming foods fortified with B12 or a B12-containing supplement (IOM, 1998, p

28 Lowgrade inflammation promotes a catabolic environment, whereas thickening of the subchondral plates restricts exchange of nutrients and waste products within the IVD 29 eventually leading to NP cell senescence