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Blom HJ, Engelen DPE, Boers GHJ, Stadhouders AM, Sengers RCA, De Abreu R, TePoele-Pothoff MTWB, and Trijbels JMF (1992)

2024;96:e29333

[iii] However, there are challenges in extrapolating the preclinical data to humans and a risk that the animal model does not encompass all characteristics of a medical condition affecting humans