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"It's preliminary, but you can see that countries that have more ergothioneine in their diets, countries like France and Italy, also have lower incidences of neurodegenerative diseases, while people in countries like the United States, which has low amounts of ergothioneine in the diet, have a higher probability of diseases like Parkinson's Disease and Alzheimer's ," said Beelman

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Notably, NADPH depletion sensitizes fibrosarcoma HT-1080 cells to ferroptosis inducers, indicating that NADPH is negatively associated with ferroptosis sensitivity (48)

It helps neutralize toxins, pesticides, heavy metals, and other harmful compounds, thus supporting liver function and well-being