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Deficiency is more common than you might think, especially in people with limited meat intake, digestive disorders, or high demands during pregnancy

When to seek urgent dental or medical care Seek prompt assessment if you experience: Sudden or unexplained metallic taste lasting more than two weeks Bleeding gums, swelling or persistent discomfort Severe dry mouth or difficulty swallowing Signs of oral thrush, such as white patches or burning Persistent bad breath with metallic taste Symptoms of infection, including fever Metallic taste combined with numbness, altered speech or facial weakness These may indicate underlying conditions requiring prompt treatment

The asynchronous variant rs2070600 (Gly82Ser), which is linked to both cancer risk and changes in circulating sRAGE, was used as a surrogate marker in a 2016 Mendelian randomized meta-analysis study [9] to infer a potential causal relationship, suggesting that lowered circulating sRAGE concentrations through genetic mechanisms may increase cancer risk