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This year, shell be appearing in Aaron Sorkins directorial debut

Without large scale, on-going campaigns that reach large proportions of the population with unforgettable, motivating information about why smoking is so harmful, the core driver of quitting and not starting smoking may wane

A similar mechanism of tau toxicity has been observed in the K369I FTD tau mutant mouse, where K369I tau was shown to bind to and trap the kinesin motor adapter JIP1 thus disrupting the transport of mitochondria and other distinct cargos (Ittner et al , 2008, 2009)

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