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E2E1-NPs induce potent neutralizing antibody responses in rabbits To assess the immunogenicity of E2E1-NPs, we immunized rabbits twice, at weeks 0 and week 4, with 10 g E2 monomers, 22 g E2E1-I53-50A trimers or 27 g E2E1-NPs, resulting in equimolar amounts of E2, adjuvanted in squalene emulsion (Fig

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They are not intended to diagnose, treat, cure, or prevent disease and should not replace primary care, urgent care, emergency care, or lab-guided medical evaluation when needed

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The Centers for Disease Control and Prevention (CDC) recommends that people ages 5 and older get booster shots after completing the primary series, or first dose(s)