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doi:10.1016/j.jacc.2018.02.072 Shu XJ, Li ZF, Chang YW, Liu SY, Wang WH

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Further exploration found that ISA could lower the plasma levels of IL-6 and TNF-, which are also closely associated with depression (Wang et al., 2023

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elegans 5 has emerged as a highly effective system for whole-organism high-throughput genetic 6,7,8,9,10,11,12,13,14 and drug 15,16,17,18,19 screening

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These findings suggest that KDS12025 has the potential to pharmacologically activate the pseudoperoxidase activity of Hb, enabling effective H 2 O 2 decomposition events at minimal Hb levels

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Mitochondria affect ferroptosis at the level of the cytosolic iron pool regulation by fine-tuning the iron influx from the cytosol into mitochondria, at the level of electron transport chain by adjusting mitROS generation and oxidative phosphorylation via AMPK activation in the energy-deficient state, and at the level of tricarboxylic acid (TCA) cycle affecting the content of NADPH and GSH [162, 166]

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