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[3] This process involves soluble enzymes and chemical intermediates, differing from oxidative phosphorylation and photophosphorylation, which rely on membrane-bound enzymes and transmembrane proton gradients

Higher doses up to 15-20 mg have been used, but research suggests that exceeding 15 mg weekly doesn't consistently produce better outcomes and may increase side effects like fatigue or mild nausea[2]

-aminobutyric acid from Lactobacillus reuteri alleviates pathology by activating the Akt/GSK3/GPX4 axis (129), emodin upregulates the mitochondrial protein ubiquitin-cytochrome C reductase core protein 1 to suppress ferroptosis (130) and corilagin protects neurons by regulating the Toll-like receptor 4/Src/NOX2 pathway (131)

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Zakynthinos, Ourania Katsarou, Eva Kassi, Vaia Lambadiari, Dimitris Tousoulis, Manolis Vavuranakis, Gerasimos Si International Journal of Molecular Sciences.2023