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Rating: 4.3699 (20 reviews)

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Description

Cell culture studies using adipocytes have shown that NNMT overexpression promotes lipid accumulation and insulin resistance, while NNMT knockdown or inhibition increases NAD+ levels, activates SIRT1, enhances mitochondrial respiration, promotes expression of thermogenic genes including UCP1, and drives white adipocyte browning toward a beige phenotype

And now youre probably wondering how we know about this effect, given that this drug has been FDA-Approved for patients with blood and clotting disorders