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Further innovations involving genetically engineered biosensors such as SoNar, which are designed to monitor NAD + /NADH ratios in live cells, specifically targeting mitochondrial SoNar or the cytosolic SoNar, have been reported

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Deletion of another metabolizing gene UGT2B17 (uridine diphosphoglucuronosyltransferase) has been shown to adaptively increase in frequency in East-Asian populations [26]