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Cell (2009) 139:87190

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The reported outcome of this campaign was a candidate that retained agonist activity at amylin/calcitonin-family receptors while displaying a markedly extended pharmacokinetic profile in the authors' preclinical models, and reduced food intake in rodent models following administration

It can also help protect against atherosclerosis 31 , or hardening of the arteries, a major cause of heart disease

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