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Table 2 Comparative analysis of metal-mediated RCD pathways

Van Haren R, SG &

10.1016/j.envres.2021.111968 44 Di FraiaA.Dal PoggettoG.SalamoneM.CarraturoF.ContursiP.GuidaM.et al (2025)

In human endothelial cells and animal models, empagliflozin enhances mitochondrial membrane potential, reduces mtROS production, and upregulates antioxidant enzymes (e.g., SOD2, catalase) via AMPK and Nrf2 activation