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(ii) Efferent parasympathetic signaling triggered by NPs in brainstem, which contribute to airway inflammation and bronchoconstriction through the release of neurotransmitters such as acetylcholine (ACh) and neuropeptides in airways (iii) CRH signaling that activates LC/NE-ANS and HPA axis, which increases the airway inflammation through the secretion neurotransmitters like norepinephrine, epinephrine, and glucocorticoids (iv) NE/IL-1 signaling axis augment airway inflammation

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Furthermore, dialkylamino-coumarin is a class of dye known for their low quantum yields

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