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Approximately 40% of colon cancer patients have KRAS mutations, and patients with KRAS G13D have a poor prognosis, including susceptibility to metastasis and short survival time, while anti-EGFR therapy offers little benefit

Both in vitro and animal models indicate that selenium enhances GPx and TrxR activity within mitochondria, neutralizing ROS and preventing lipid peroxidation of mitochondrial membranes [26,65]

BPC 157 acts as a membrane stabilizer and free radical scavenger and reduces leaky gut syndrome, as shown in gastrointestinal tract cytoprotective studies (Park et al., 2020)

(7) Studies have examined changes in oxygen consumption, substrate utilization, and thermogenesis following NNMT inhibition