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To enhance the stability and avoid the premature delivery of drugs, hydrophobic drugs covalently attached to the polymer has been explored

10.1002/chem.200903584 Zhang L, Zheng Y, Xi Z, Luo Z, Xu X, Wang C, Liu Y: Metal ions binding to recA inteins from Mycobacterium tuberculosis

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Agarwal and his team concluded that skin darkening is a key sign of underlying blood and neurological issues linked to B12 deficiency