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Bernecker et al., 2011

Moreover, Cu serves as an important cofactor for enzymes such as CuSOD, cytochrome C oxidase (99)

When functioning as an HDAC inhibitor, butyrate treatment increases histone H3 lysine 9 acetylation, upregulating transcription of glucose metabolism-related genes like glucose transporter type 4 (GLUT4), monocarboxylate transporter 1 (MCT-1) [68], consequently enhancing glucose uptake with possible secondary stimulation of fatty acid synthesis in muscle cells