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Conclusion NPT1, NPT4, ABCG2 expressed on the apical membrane and OAT1, OAT3 expressed on the basolateral membrane have been confirmed to contribute to the secretory transport of urate from proximal tubular epithelial cells into the tubule lumen (Wen et al., 2020)

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it is used by cells to regulate cell development and metabolism, but can also be used to turn off the expression of foreign genes, such as those of an invading virus

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Zinc has also been implicated in modulating deiodinase activity, particularly type 1 deiodinase in peripheral tissues