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& Dintzis, S

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Passive loading techniques depend on the ability of the liposomes to encapsulate a certain amount of aqueous solute and solvent during the formation of the vesicle, whereas active loading techniques involve methods for encapsulating amphiphilic compounds as they can rapidly permeate through the lipid bilayer

An important check on our model was to compare its predictions on patient outcomes to the empirical data and modeling results presented in[10]