I told my wife, Over the break, it would be funny if I just got a Buddy the Elf costume and didnt shave for a week, and Im just sitting there with a candy cigarette and Im just gonna sit there for a period and see how people react.' Popular on Variety The reaction was insane! Ferrell said
Klyden delivers the scene's most quoted line: "I feel as if I've been standing my entire life and I just sat down"

Nomenclature ABTS 2,2Azinobis(3ethylbenzthiazoline6sulphonic acid) ADC Arginine decarboxylase AntiTMV Antitobacco mosaic virus CHT Chemma tobacco DPPH 2,2Diphenyl1picrylhydrazylhydrate EPC Endothelial progenitor cells FRAP Ferric reducing antioxidant power JAT1 and JAT2 Jasmonateinducible alkaloid transporters 1 and 2 IARC International Agency for Research on Cancer MATE 1 and 2 Multidrug and toxic compound extrusion 1 and 2 MRSA Methicillinresistant Staphylococcus aureus nAChRs Nicotinic acetylcholine receptors NCI National Cancer Institute NUP1 Nicotine uptake permease 1 OGD Oxygenglucose deprivation PAH Polycyclic aromatic hydrocarbons SLT Smokeless tobacco ST Smoking tobacco TNF Tumor necrosis factoralpha TSNAs Tobaccospecific nitrosamines USDA United States Department of Agriculture WHO World Health Organization Author Contributions Comprehensive literature review, writingoriginal draft, visualization, and revision and editing the manuscript: Abir Chami

Lewis enlisted the help of such admirers as Sir Mick Jagger, Keith Richards, Kris Kristofferson, Willie Nelson and Buddy Guy for his 2006 release Last Man Standing
Measures 10.25H x 9.25W in