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Description

GCLC, HSBP1 and ACSF2 are independent prognostic FRGs in pRCC (120, 121)

ZhuMLiuXYeYYanXChengYZhaoLet al

The first step is mediated by -glutamylcysteine synthetase (GCLC), which catalyzes the -amide bond between the -carboxyl group of glutamate and the amino group of cysteine to form -glutamyl-cysteine (-Glu-Cys)