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Description

J Minim Invasive Gynecol (2017) 24(3):47884

Cyst(e)ine and GPX4 inhibition as therapeutic targets To exploit our findings in vivo, we first tested simultaneous inhibition of cysteine uptake and transsulfuration in vitro using IKE, an erastin analog with acceptable pharmacokinetic properties 40,41 , and PPG 33 (Fig