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For functional profiling, bwa-mem was used with the default setting to align the preprocessed reads against the integrated gene catalog (IGC), a comprehensive database comprising 9,879,896 genes specific to the human gut microbiome functionality [41, 42]

In our simulations (Figure7, panels A and B) liver GSH declines to 70% of normal and plasma GSH declines to 88% of normal

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10.1182/blood-2012-05-432088 85 Ventura-ClapierR.GarnierA.VekslerV

10.3390/ijms21072358 89 RutterB