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To further test whether this effect is mediated by periodontitis-induced N1-polarized BM neutrophils, BM neutrophils from control and ligatured WT donor mice were adoptively transferred into db/db recipient mice (Con-Neus and Lig-Neus) (Fig S8a)

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Although elevated IgG is a hallmark of AIH, but can be falsely elevated in acute liver failure and ACLF due to non-specific immune response to liver injury, infection, and systemic inflammation [48, 49]