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doi: 10.1016/j.bbi.2016.07.002 58 GaliciR.BoggsJ

Overcoming these events can be achieved by adding dopamine agonists (such as pramipexole and ropinirole), changing the formulation of levodopa, changing the administration regimen, or adding amantadine

Results may last 8 - 10 months, depending on the patient's age, condition, and lifestyle

IGFBPs have higher affinity for IGF-1 than do IGF-1 receptors and the conversion of IGF-1 to des-IGF-1 is associated with a low binding protein affinity 5

Funding This work was funded by two grants from the Deanship of Scientific Research and Graduate Studies, Applied Science Private University, Amman, Jordan (DRGS/2024/11), and Princess Nourah bint Abdulrahman University Researchers Supporting Project Number (PNURSP2026R305), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia