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In addition to its direct antimycobacterial activity, BA promotes bacterial clearance during mycobacterial infection through the activation of the NRF2KEAP1 and HO-1 signaling pathways ( Figure 3 )

In a vicious circle, feeding itself, SARS-CoV-2 may aggravate the evolution of atherosclerosis as a result of excessive and aberrant plasmatic concentration of cytokines (Vinciguerra et al., 2020

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The complications of Labial Melanotic Macules may include the following: The longstanding skin patches can cause emotional stress and cosmetic concerns in some individuals The appearance of the pigmented macules may induce a fear of melanoma (which is a type of skin cancer) Complications that arise from an underlying genetic condition/syndrome How is Labial Melanotic Macules Treated

PMID 26942189