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Studies have demonstrated that carnosine exhibits significant protective effects across multiple disease systems (Fig

Garnero P, Shih WJ, Gineyts E, Karpf DB, Delmas PD (1994) Comparison of new biochemical markers of bone turnover in late postmenopausal osteoporotic women in response to alendronate treatment

doi:10.5301/ijao.5000024

One possible explanation of the beneficial actions of methotrexate in RA is the diminution of both the size and reactivity of the T-lymphocyte population