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In the following articles, I discuss in-depth what measures should be taken to help correct a Slow COMT variant: Why I DO NOT Recommend Multivitamins The Case of Copper MTHFRSolve What Supplements Should You Take if You Have a COMT Mutation

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The most consistently reported pathway involves VEGFR2 and the Akt-eNOS nitric oxide cascade

IV Infusion Therapy may be used as an adjunct to conventional medicine or as the sole treatment modality depending on what is determined optimal for the patient