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Baicalein reduces iron levels, LPO generation, and morphological characteristics associated with ferroptosis in the brain tissues of MCAO mice ( Escherichia coli hydrolyzed baicalin to baicalein and oroxylin A ( Baicalin (PubChem CID: 64982) is a flavonoid compound with the molecular formula C 21 H 18 O 11

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In a feeding study involving 45 healthy subjects, the mean conversion rate of glucosinolates (of which 85% was glucoraphanin) to dithiocarbamates over a 24-hour period was estimated to be around 12% with wide variations among participants (range, 1.1 to 40.7%) (6)

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To further examine this relationship, the data were plotted in a graph of cell viability against relative basal glutathione levels and a linear relationship was observed with a statistically significant r value of 0.9995 confirming a correlation between glutathione and cisplatin resistance (Fig