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Hidroxocobalamina: Habitual en inyectables

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based on consistent formation of -helical structure in initial rounds of structure calculations in which no hydrogen bond restraints were defined), inter-molecular PRE restraints (4 non-interacting copies of the spin label to account for different spin label orientations), inter- and intra-molecular NOE restraints, and ambiguous distance restraints for residues showing CSPs upon binding

Clinical context Statins are used for the primary and secondary prevention of cardiovascular disease and are among the most commonly prescribed medicines