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Endogenous Antioxidants All cells contain antioxidant systems that specifically detoxify superoxide or hydrogen peroxide or contribute to the defense against ROS (Figure 2)

Furthermore, the overlapping values of F 510 /F 580 between the GSH-low and GSH-high populations (compare Figs

Such designs will also be essential for distinguishing PAC-intrinsic effects of mitophagy from indirect consequences mediated by inflammatory cells, endothelial injury, or systemic metabolic stress

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This pathway yields NADPH, which is essential for converting oxidized glutathione back to its reduced form