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doi: 10.1172/jci.insight.122299 287 ScholzGJandusCZhangLGrandclmentCLopez-MejiaICSonesonCet al

Nat Commun 11:3412

For tesamorelin, known adverse effects (based on US and Canadian prescribing information, as no UK Summary of Product Characteristics exists) include: Fluid retention (oedema, joint pain, carpal tunnel syndrome) Elevated blood glucose and reduced insulin sensitivity due to GH elevation Injection site reactions Raised IGF-1 levels active malignancy is a key contraindication

It has also been noted that patients with PTLD can have deficits in mental activation or information processing speed when initiating a cognitive process, independent of sensory, perceptual, or motor deficits (131)