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selenium is a component of the antioxidant enzyme glutathione peroxidase, which helps to fight cell-damaging free-radicals

Interestingly, the LIN28B/MYC/miR-34a-5p pathway can be therapeutically exploited: in fact, when using LIN28B inhibitors, miR-34a-5p increases and PKM2 decreases while tumor growth and lung metastasis are suppressed [42]