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Endometriosis involves significant fibrosis, and anti-fibrotic effects could theoretically reduce adhesion formation and tissue scarring that contributes to pain and organ dysfunction

Immunoblot analysis showed FASN protein levels were substantially decreased in a dose-dependent manner with Chac1 overexpression (Figure 5L), indicating this effect by GSH depletion is intrinsic to hepatocytes

Inhibition of cystine input inhibits the synthesis of GSH in cells to the large extent and induces ferroptosis

& Shadel, G

GW-501516 treatment increased expression of carnitine palmitoyl transferase 1a, the rate-limiting enzyme of fatty acid oxidation, in activated T cells