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This hydrogel demonstrated a sustained release profile of magnesium ions, which was shown to alleviate IDD by promoting the synthesis of ECM and modulating the inflammatory microenvironment associated with IDD

Diagnostic Criteria and Phenomenology of Peripherally-Induced Movement Disorders Cardoso and Jankovic proposed the diagnostic criteria for PIMD, which has three core components: (a) severity of the trauma (should be severe enough to cause local symptoms for at least two weeks or requires medical evaluation within two weeks after trauma, (b) location of the trauma (body part with the involuntary movements should be anatomically related to the site of trauma, and (c) onset of the movement disorder (should be within days or months, up to one year after the injury) [ 2 , 16 ]

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Long-term therapy: Designed for ongoing use, not a short-term cycle. Supervision required: As a clinical-stage drug, dosing outside trials is not standardized and should be overseen by medical professionals