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Therefore, low-dose chelation strategies are preferred to maintain neuroprotection without disrupting systemic iron balance

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Reading the unique DNA methylation landscape of the brain: non-CpG methylation, hydroxymethylation, and MECP2

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While there are different models to study glutathione metabolism, in this study we used BSO as it is a specific and potent chemical inhibitor of the rate limiting enzyme GCLC (38)