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This paper identified oligodendrocyte lineage cell responses associated with remyelination failure in multiple sclerosis lesions at different stages of damage and repair, identifying oligodendrocyte loss as a feature of poor remyelination in chronic lesions

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LC-MS/MS conditions The analyte molecules were eluted on Zorbax XDB-C18 column (3.5 m, 2.1x20 mm) with the mobile phase composed of water/0.1% formic acid and methanol/0.1% formic acid in the ratio of 70:30 V/V with the flow rate of 0.2 ml/min

P., Schultz G

Research protocols typically use 250 to 500 mcg administered subcutaneously once or twice daily for 4 to 8 weeks