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To nd out the implica- tion of the serotonin path ways in OCD, they performed pretreatment administering of 300 mg/kg of p-chlorophenyl alanine (PCPA), a serotonin depleting agent, for three con- secutive days and 24h, followed by 600 mg/kg of MEBH or 15 mg/kg of uoxetine

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