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the cited rationale is avoiding insulin spikes that may compete with lipolytic signaling

In a phase I, bronchioloalveolar delivery of INGN-201 lead to stable disease in 16 of 21 patients with BAC, albeit p53 status was not an entry criterion (77)

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After repeated IM administration of BPC157 at 30 g/kg for seven consecutive days, the plasma concentration versus time curve was similar to that observed after a single IM injection of 30 g/kg (Figure 2C)

Some scholars have identified and validated prognostic gene signatures of GC and built up a specific score formula to measure the risk, but these signatures had not been widely accepted or put into practice [34]