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Description

AMPK and NRF2: interactive players in the same team for cellular homeostasis

The binding pose of isoxazole 1 was inserted into the crystal structure of Ca Acs2 bound to an alkyl-AMP ester (PDB 8W0B) via structural alignment with isoxazole 1 -bound Cn Acs1

For example, cerebrospinal fluid could be sampled at both timepoints in a study measuring cognitive performance at baseline and during post-exercise symptom provocation