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Description

Glutathione is synthesized in all mammalian cells

Wakeman M, Archer DT

This causes excessive calcium influx into cells, triggering more oxidative stress and mitochondrial dysfunction and resulting in apoptosis or RGC death

FASEB Journal (1997) 7

Research with 5-Amino-1MQ has examined whether inhibiting NNMT in these contexts alters adipocyte biology, lipid metabolism, and broader adipose tissue function